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For Adults:

If you struggle with
treatment-resistant depression,
there's somewhere to turn.

 

SPRAVATO™ nasal spray is a different kind of medication taken with an oral antidepressant for adults with treatment-resistant depression – a first in decades approved by the FDA.

If you’ve struggled with depression and tried two or more antidepressants* in your current episode without adequate relief, talk to your doctor to see if you have treatment-resistant depression.

*Of adequate dose and duration.


Ask your doctor if SPRAVATO™ may be an option for you.

 

In a clinical study of adults with 
treatment-resistant depression:

Those who took SPRAVATO™ and an oral antidepressant experienced greater reductions of depression symptoms at four weeks compared to those who received a placebo plus an oral antidepressant.

Based on an overall score on a standardized rating scale.

Most common side effects of SPRAVATO™:

Dissociation, dizziness, nausea, sedation, spinning sensation, reduced sense of touch and sensation, anxiety, lack of energy, increased blood pressure, vomiting and feeling drunk.

If these common side effects occur, they usually happen right after taking SPRAVATO™ and go away the same day.

These are not all the possible side effects of SPRAVATO™. Learn more about possible side effects here.

SPRAVATO™ is only available at certified SPRAVATO™ treatment centers under the supervision of a healthcare professional.

Because of the risks for sedation, dissociation and abuse and misuse, your doctor will enroll you in the SPRAVATO™ Risk Evaluation and Mitigation Strategy (REMS) Program.

 

Robin P., Berkeley, California:

Robin is a real patient with treatment-resistant depression and has been compensated for her time by Janssen Pharmaceuticals, Inc.

“When you’re depressed, you forget about the little things you used to enjoy. I’ve been doing a lot of catching up now that I’m feeling better.”

Individual results may vary.

SPRAVATO™ works differently than other medications to target treatment-resistant depression.

SPRAVATO™ is taken with an oral antidepressant.

Frequently Asked Questions