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How To Use SPRAVATO® Nasal Spray & SPRAVATO® Dosing | SPRAVATO® (esketamine) Nasal Spray

How to Use SPRAVATO® Nasal Spray

SPRAVATO® Nasal Spray Device

Instructions for Use

You will administer SPRAVATO® nasal spray yourself under the supervision of a healthcare provider at a certified SPRAVATO® treatment center. Your healthcare provider will show you how to use the SPRAVATO® nasal spray device.

 

Download Step-by-Step Instructions for Use

SPRAVATO® Dosing for
Treatment-Resistant Depression

After you and your healthcare provider have decided SPRAVATO® is right for you —
and you understand the benefits and risks — you can start planning for treatment.

Weeks 1-4, Weeks 5-8 and Weeks 9+ schedules
  • SPRAVATO® is taken with an oral antidepressant
  • You administer SPRAVATO® nasal spray yourself under the supervision of a healthcare provider at a certified SPRAVATO® treatment center
  • SPRAVATO® is taken twice a week for the first four weeks
  • After the first four weeks, you and your doctor will discuss and determine if treatment should be continued and the dose and how often you’ll receive SPRAVATO®

If two or more antidepressants haven’t worked for you, you may have treatment-resistant depression (TRD). It’s time to talk to your doctor about a different treatment approach.