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SPRAVATO® (esketamine): A Prescription Nasal Spray | SPRAVATO®
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SPRAVATO®, the only FDA-approved nasal spray for adult patients with two forms of challenging-to-treat major depressive disorder (MDD):

  • Adults with MDD who’ve had an inadequate response to two or more oral antidepressants, known as treatment-resistant depression (TRD)
  • Depressive symptoms in adults with MDD with suicidal thoughts or actions (MDSI)

See Limitations of Use below